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Bio-Techne corporation α2 macroglobulin
Inhibitors and cofactors of the common and Protein C pathways in SARS‐CoV‐2 infection and controls. (A) Antithrombin, (B) TAT, Thrombin‐Antithrombin complex, (C) Heparin Cofactor II, (D) Protease Nexin‐1, (E) <t>α2‐macroglobulin,</t> (F) Protein Z, (G) Protein Z Inhibitor, (H) Protein C, (I) Protein S (total), and (J) Protein C Inhibitor plasma concentrations were determined by ELISA in controls and COVID‐19 patients. Each symbol corresponds to one patient. Means and SEM are indicated. NS, non‐significant; * p ≤ 0.05; **** p ≤ 0.0001 (Kruskal‐Wallis test, or Mann‐Whitney U test).
α2 Macroglobulin, supplied by Bio-Techne corporation, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Alomone Labs human probdnf-biotin
Inhibitors and cofactors of the common and Protein C pathways in SARS‐CoV‐2 infection and controls. (A) Antithrombin, (B) TAT, Thrombin‐Antithrombin complex, (C) Heparin Cofactor II, (D) Protease Nexin‐1, (E) <t>α2‐macroglobulin,</t> (F) Protein Z, (G) Protein Z Inhibitor, (H) Protein C, (I) Protein S (total), and (J) Protein C Inhibitor plasma concentrations were determined by ELISA in controls and COVID‐19 patients. Each symbol corresponds to one patient. Means and SEM are indicated. NS, non‐significant; * p ≤ 0.05; **** p ≤ 0.0001 (Kruskal‐Wallis test, or Mann‐Whitney U test).
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Innovative Therapies gla-domainless factor xa (gdfxa) sequestered within human α2-macroglobulin (α2m)
Inhibitors and cofactors of the common and Protein C pathways in SARS‐CoV‐2 infection and controls. (A) Antithrombin, (B) TAT, Thrombin‐Antithrombin complex, (C) Heparin Cofactor II, (D) Protease Nexin‐1, (E) <t>α2‐macroglobulin,</t> (F) Protein Z, (G) Protein Z Inhibitor, (H) Protein C, (I) Protein S (total), and (J) Protein C Inhibitor plasma concentrations were determined by ELISA in controls and COVID‐19 patients. Each symbol corresponds to one patient. Means and SEM are indicated. NS, non‐significant; * p ≤ 0.05; **** p ≤ 0.0001 (Kruskal‐Wallis test, or Mann‐Whitney U test).
Gla Domainless Factor Xa (Gdfxa) Sequestered Within Human α2 Macroglobulin (α2m), supplied by Innovative Therapies, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Sino Biological α2 m
Inhibitors and cofactors of the common and Protein C pathways in SARS‐CoV‐2 infection and controls. (A) Antithrombin, (B) TAT, Thrombin‐Antithrombin complex, (C) Heparin Cofactor II, (D) Protease Nexin‐1, (E) <t>α2‐macroglobulin,</t> (F) Protein Z, (G) Protein Z Inhibitor, (H) Protein C, (I) Protein S (total), and (J) Protein C Inhibitor plasma concentrations were determined by ELISA in controls and COVID‐19 patients. Each symbol corresponds to one patient. Means and SEM are indicated. NS, non‐significant; * p ≤ 0.05; **** p ≤ 0.0001 (Kruskal‐Wallis test, or Mann‐Whitney U test).
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Millipore α2-macroglobulin from human plasma 441251
Inhibitors and cofactors of the common and Protein C pathways in SARS‐CoV‐2 infection and controls. (A) Antithrombin, (B) TAT, Thrombin‐Antithrombin complex, (C) Heparin Cofactor II, (D) Protease Nexin‐1, (E) <t>α2‐macroglobulin,</t> (F) Protein Z, (G) Protein Z Inhibitor, (H) Protein C, (I) Protein S (total), and (J) Protein C Inhibitor plasma concentrations were determined by ELISA in controls and COVID‐19 patients. Each symbol corresponds to one patient. Means and SEM are indicated. NS, non‐significant; * p ≤ 0.05; **** p ≤ 0.0001 (Kruskal‐Wallis test, or Mann‐Whitney U test).
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ICN Biomedicals anti-human α2-macroglobulin antibody icn biomedicals cat. no. 55113
Inhibitors and cofactors of the common and Protein C pathways in SARS‐CoV‐2 infection and controls. (A) Antithrombin, (B) TAT, Thrombin‐Antithrombin complex, (C) Heparin Cofactor II, (D) Protease Nexin‐1, (E) <t>α2‐macroglobulin,</t> (F) Protein Z, (G) Protein Z Inhibitor, (H) Protein C, (I) Protein S (total), and (J) Protein C Inhibitor plasma concentrations were determined by ELISA in controls and COVID‐19 patients. Each symbol corresponds to one patient. Means and SEM are indicated. NS, non‐significant; * p ≤ 0.05; **** p ≤ 0.0001 (Kruskal‐Wallis test, or Mann‐Whitney U test).
Anti Human α2 Macroglobulin Antibody Icn Biomedicals Cat. No. 55113, supplied by ICN Biomedicals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Novo Nordisk human α2-macroglobulin
Inhibitors and cofactors of the common and Protein C pathways in SARS‐CoV‐2 infection and controls. (A) Antithrombin, (B) TAT, Thrombin‐Antithrombin complex, (C) Heparin Cofactor II, (D) Protease Nexin‐1, (E) <t>α2‐macroglobulin,</t> (F) Protein Z, (G) Protein Z Inhibitor, (H) Protein C, (I) Protein S (total), and (J) Protein C Inhibitor plasma concentrations were determined by ELISA in controls and COVID‐19 patients. Each symbol corresponds to one patient. Means and SEM are indicated. NS, non‐significant; * p ≤ 0.05; **** p ≤ 0.0001 (Kruskal‐Wallis test, or Mann‐Whitney U test).
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Athens Research human α2 macroglobulin
Inhibitors and cofactors of the common and Protein C pathways in SARS‐CoV‐2 infection and controls. (A) Antithrombin, (B) TAT, Thrombin‐Antithrombin complex, (C) Heparin Cofactor II, (D) Protease Nexin‐1, (E) <t>α2‐macroglobulin,</t> (F) Protein Z, (G) Protein Z Inhibitor, (H) Protein C, (I) Protein S (total), and (J) Protein C Inhibitor plasma concentrations were determined by ELISA in controls and COVID‐19 patients. Each symbol corresponds to one patient. Means and SEM are indicated. NS, non‐significant; * p ≤ 0.05; **** p ≤ 0.0001 (Kruskal‐Wallis test, or Mann‐Whitney U test).
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Inhibitors and cofactors of the common and Protein C pathways in SARS‐CoV‐2 infection and controls. (A) Antithrombin, (B) TAT, Thrombin‐Antithrombin complex, (C) Heparin Cofactor II, (D) Protease Nexin‐1, (E) α2‐macroglobulin, (F) Protein Z, (G) Protein Z Inhibitor, (H) Protein C, (I) Protein S (total), and (J) Protein C Inhibitor plasma concentrations were determined by ELISA in controls and COVID‐19 patients. Each symbol corresponds to one patient. Means and SEM are indicated. NS, non‐significant; * p ≤ 0.05; **** p ≤ 0.0001 (Kruskal‐Wallis test, or Mann‐Whitney U test).

Journal: EJHaem

Article Title: SARS‐CoV‐2 infection results in upregulation of Plasminogen Activator Inhibitor‐1 and Neuroserpin in the lungs, and an increase in fibrinolysis inhibitors associated with disease severity

doi: 10.1002/jha2.654

Figure Lengend Snippet: Inhibitors and cofactors of the common and Protein C pathways in SARS‐CoV‐2 infection and controls. (A) Antithrombin, (B) TAT, Thrombin‐Antithrombin complex, (C) Heparin Cofactor II, (D) Protease Nexin‐1, (E) α2‐macroglobulin, (F) Protein Z, (G) Protein Z Inhibitor, (H) Protein C, (I) Protein S (total), and (J) Protein C Inhibitor plasma concentrations were determined by ELISA in controls and COVID‐19 patients. Each symbol corresponds to one patient. Means and SEM are indicated. NS, non‐significant; * p ≤ 0.05; **** p ≤ 0.0001 (Kruskal‐Wallis test, or Mann‐Whitney U test).

Article Snippet: DUOSet enzyme‐linked immunosorbent assay (ELISA) performed for Kallistatin (SERPINA4, DY1669), Plasminogen Activator Inhibitor‐1 (PAI‐1, SERPINE1; DY1786), Protein Z Inhibitor (PZI, SERPINA10; DY8115), α2‐Macroglobulin (A2M; DY1938), Protease Nexin‐2/Amyloid Beta Precursor Protein (PN2/AβPP; DY850) and C1‐Inhibitor (C1‐INH, SERPING1; DY2488) from Bio‐Techne/R&D (Minneapolis, MN).

Techniques: Infection, Enzyme-linked Immunosorbent Assay, MANN-WHITNEY

Univariate logistic regression of association of covariates with moderate and severe diseases

Journal: EJHaem

Article Title: SARS‐CoV‐2 infection results in upregulation of Plasminogen Activator Inhibitor‐1 and Neuroserpin in the lungs, and an increase in fibrinolysis inhibitors associated with disease severity

doi: 10.1002/jha2.654

Figure Lengend Snippet: Univariate logistic regression of association of covariates with moderate and severe diseases

Article Snippet: DUOSet enzyme‐linked immunosorbent assay (ELISA) performed for Kallistatin (SERPINA4, DY1669), Plasminogen Activator Inhibitor‐1 (PAI‐1, SERPINE1; DY1786), Protein Z Inhibitor (PZI, SERPINA10; DY8115), α2‐Macroglobulin (A2M; DY1938), Protease Nexin‐2/Amyloid Beta Precursor Protein (PN2/AβPP; DY850) and C1‐Inhibitor (C1‐INH, SERPING1; DY2488) from Bio‐Techne/R&D (Minneapolis, MN).

Techniques: